Tuesday 16 January 2018

OUGD505: Alternatives To Animal Testing

As so many brands don't test on animals, its important for the alternatives to be known- these could even be incorporated into my design.

IN VITRO TESTING

Harvard's Wyss Institute created 'organs-on chips', these are human cells grown in a system to mimic the structure and function of human organs and organ systems. These chips are often used in drug testing and toxicity testing, they replicate human physiology, diseases and drug responses more accurately than animals.

COMPUTER (in silico) MODELING 

This is a developed range of computer models created by researchers that stimulate human biology and the profession of developing diseases. These studies show that they can accurately predict the ways that new drugs will react in the human body and replace the use of animals in exploratory research and many standard drug tests.

RESEARCH WITH HUMAN VOLUNTEERS

A method called 'microdosing' can provide vital information on the safety of an experimental drug. The volunteers are given an extremely small one-time drug dose and imaging techniques are used to monitor how it behaves in the body.

HUMAN-PATIENT SIMULATORS

Life-like computerised human-patient simulators that breathe, bleed, convulse, talk and even die have been shown to teach students physiology and pharmacology. These are used in 97% of medical schools across the U.S therefore students are no longer required to cut into any animals

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